Endocrine Abstracts

Objective: Assessment of the health status in a population from a territory with apparently normal iodine intake may take in consideration the incidence of goiter as a mass pathologic process. Considering goiter as a result of both endogenous and exogenous factors, the study of its incidence and correlations with potentially goitrogens represents a prophylactic medical activity. Use of the term ‘paraendemic’ for a certain territory does not justify a ‘relaxation...

Introduction: Involvement of growth hormone in the maturation and function of the ovary is proved by a series of clinical observations.Scope: Assessing serum levels of IGF1 as a marker of GH activity correlated to age of onset of menarche and menopause.Method: The study groups consisted of 41 patients (group 1) with GH deficiency diagnosed before the age of 8 years and a group of 18 adult patients with pituitary dwarfism who had ea...

Objectives: Hyperthyroidism in pregnancy presents a challenge for medical doctor, patient and products of conception.Aim of the study: To specify the peculiarities of expression of hyperthyroidism in pregnant women, diagnosis, monitoring, treatment, prognosis of pregnancy and effect on the fetus.Materials and methods: The study included a total of 27 women with hyperthyroidism of which 15 (group A) had thyrotoxicosis before concept...

Aims: Presence of antinuclear antibodies (ANA) is correlated to tissue involutive lesions by microvascular alterations. The possible involvement of hypovitaminosis D as a negative immunomodulatory factor along with the presence of ANA and the incidence of chronic autoimmune thyroiditis (CAT) atrophic form is a complex mechanism with multiple pathological intercorrelations.Material and method: Inclusion criteria: patients - new cases diagnosed with CAT wi...

Objectives: Evaluation of functional thyroid alterations in correlation with hyperemesis gravidarum (HG).Material and method: Study performed on a group of 136 pregnant women with HG and a control group of 101 pregnant women. In both groups, cases with a known history of thyroid disease, molar pregnancy, multiple pregnancies or other systemic chronic diseases were excluded. Patients were clinically and serologically examined (TSH, FT4, ATPO, TRAb), the r...

Introduction: Dento-maxillary system changes associated to thyroid disorders are constantly present. Differentiated impairment, depending on the period of evolution of the disease, explains the high percentage of over 60% of cases with parodonthopathy.Aim of the study: Evaluating the oro-maxillo-facial changes in patients with underdose treated hypothyroidism.Methods: The study group comprised 154 patients with hypothyroidism, 132 ...

Introduction: The incidence of depressive type psychoaffective disorders is significantly increased in patients with chronic autoimmune thyroiditis.Objectives: The study of thyroid autoimmunity correlated with serum levels of TSH, FT4 and depression degree.Methods: The study comprised 70 patients (64 women and 6 men), aged between 18 and 66 years, divided in 4 groups. All study groups were analyzed according to the degree of depres...

Introduction: Juvenile hypothyiroidism shows various complications depending on the correctitude of substitutive treatment.Aims of the study: To identify the massive facial changes with occlusive disorders, dental malpositions, altered chronology of dental eruption, periodontal changes in terms of absence of thyroid replacement therapy or drug sub-dosing.Methods: The study group comprised 24 children, 15 girls and 8 boys; 4 cases o...

Introduction: Benign breast disease is the most common reason for senology consultation.Objectives: To investigate the possible involvement of thyroid autoimmunity and hypovitaminosis D in the development of mammary echo-structural lesions.Method: The BI-RADS score was assigned to categories 1–4 characteristic of benign mastopathy, in three groups of patients: Group 1 (n=167) – with chronic autoimmune thyro...

Introduction: Relative adrenal insufficiency is considered a life threatening event, especially when associated with a serious event like trauma. Recognition and treatment of relative adrenal insufficiency is a challenge for clinical practitioner.Objectives: We wanted to study adrenal dysfunction, diagnostic methods corresponding to the emergency situation for a trauma patient, adaptative capability of hypothalamic–pituitary–adrenal axis and th...